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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRAS
All Species:
30.3
Human Site:
Y141
Identified Species:
66.67
UniProt:
P01112
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01112
NP_001123914.1
189
21298
Y141
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
Chimpanzee
Pan troglodytes
XP_521702
189
21289
Y141
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540523
226
24555
Y178
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61411
189
21330
Y141
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
Rat
Rattus norvegicus
P20171
189
21296
Y141
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P08642
189
21347
Y141
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
Frog
Xenopus laevis
Q91806
189
21364
F141
A
R
S
Y
G
I
P
F
I
E
T
S
A
K
T
Zebra Danio
Brachydanio rerio
P79737
188
21321
F140
A
R
S
Y
G
I
E
F
V
E
T
S
A
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08646
189
21575
Y141
A
K
Q
Y
G
I
P
Y
I
E
T
S
A
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P22981
184
20964
N141
A
K
G
Y
G
I
P
N
V
D
T
S
A
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P22126
213
24008
Y147
A
A
E
F
G
T
K
Y
I
E
T
S
A
K
T
Conservation
Percent
Protein Identity:
100
99.4
N.A.
81.8
N.A.
99.4
99.4
N.A.
N.A.
97.8
84.1
83
N.A.
77.2
N.A.
74.5
N.A.
Protein Similarity:
100
99.4
N.A.
83.1
N.A.
99.4
99.4
N.A.
N.A.
99.4
93.1
91.5
N.A.
85.1
N.A.
85.1
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
80
N.A.
86.6
N.A.
66.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
59.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
69
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
10
0
0
0
0
0
0
0
0
0
0
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
0
0
91
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
19
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
100
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
91
0
0
82
0
0
0
0
0
0
% I
% Lys:
0
19
0
0
0
0
10
0
0
0
0
0
0
100
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
82
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
73
0
0
0
0
0
0
0
0
100
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
100
0
0
0
100
% T
% Val:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
91
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _